The role of haematopoietic lineage cells in the TMEV model of multiple sclerosis. (360G-Wellcome-083135_Z_07_B)
This proposal addresses the role of haematopoietic lineage cells (HCs) in disease persistence and spread in a viral model of multiple sclerosis (MS). We hope to determine the cell type and route of entry of HCs into the central nervous system (CNS) using a combination of immunohistochemistry, molecular biology and 2-photon slice imaging. Using molecular biology techniques we will investigate the mechanistic hypothesis that galectin-3 is necessary for Theiler's murine encephalitis virus (TMEV) induced HC recruitment and migration.
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Grant Details
Amount Awarded | 13694 |
Applicant Surname | James |
Approval Committee | Neurosciences And Mental Health |
Award Date | 2011-08-31T00:00:00+00:00 |
Financial Year | 2010/11 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 083135/Z/07/B |
Lead Applicant | Miss Rachel James |
Partnership Value | 13694 |
Planned Dates: End Date | 2011-09-30T00:00:00+00:00 |
Planned Dates: Start Date | 2011-08-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | South East |
Sponsor(s) | Prof Andrew King |