The consequences of temporal lobe epilepsy surgery . (360G-Wellcome-083148_Z_07_Z)

£1,487,687

We will investigate the effects of temporal lobe epilepsy and surgical removal of the anterior temporal lobe on cognitive functions that involve the temporal and the frontal lobes, and mood. We will investigate the functional neuroanatomy of these processes and how the frontal and temporal lobes are interconnected in terms of function and the white matter tracts that provide structural connectivity. We will implement and evaluate methods to predict the effects of anterior temporal lobe resecti on on cognition, mood and the field of vision, and how to subsequently minimise these risks. We will advance the technology of tractography and its integration with anatomical imaging, and will use temporal lobe surgery as a test-bed to implement combined serial fMRI and tractography after cerebral insults to determine the basis of recovery and plasticity.

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Grant Details

Amount Awarded 1487687
Applicant Surname Duncan
Approval Committee Neurosciences And Mental Health
Award Date 2007-10-10T00:00:00+00:00
Financial Year 2007/08
Grant Programme: Title Programme Grant
Internal ID 083148/Z/07/Z
Lead Applicant Prof John Duncan
Other Applicant(s) Dr Pamela Thompson, Prof Matthias Koepp
Partnership Value 1487687
Planned Dates: End Date 2013-12-31T00:00:00+00:00
Planned Dates: Start Date 2008-01-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Greater London