Assessing the challenges faced by health systems in providing paediatric Cotrimoxazole prophylaxis in resource limited countries. (360G-Wellcome-085831_B_08_Z)

£73,801

HIV exposed infants are 16 times more likely to die in their second six months of life than unexposed infants, largely due to respiratory infections. Cotrimoxazole prophylaxis significantly reduces both mortality and morbidity. In Zimbabwe it is estimated that only 11% of exposed infants are prescribed cotrimoxazole and the extent to which it is correctly taken is unknown. The aim of the project is to describe the process and obstacles to provision of cotrimoxazole prophylaxis for HIV exposed infants in three sites in Zimbabwe, focusing on issues related to drug supply and adherence. This information will be used to develop an evidence-based intervention for improving its provision. The study will be conducted in three phases in two Zimbabwean health centres, one urban, one rural: 1) guidelines and standard operating procedures for PMTCT, cotrimoxazole prophylaxis and aftercare of HIV infected mothers will be studied; 2) implementation activities at study clinics including identification of HIV infected mothers, procedures for ensuring babies are prescribed cotrimoxazole and adhere to treatment will be assessed as will aftercare for HIV positive mothers; 3) the findings will be disseminated to stakeholders to identify solutions and develop an evidence based intervention relevant for Zimbabwe and the wider region

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Grant Details

Amount Awarded 73801
Applicant Surname Sibanda
Approval Committee Populations and Public Health Funding Committee
Award Date 2008-09-16T00:00:00+00:00
Financial Year 2007/08
Grant Programme: Title International Masters Fellowship
Internal ID 085831/B/08/Z
Lead Applicant Dr Euphemia Sibanda
Partnership Value 73801
Planned Dates: End Date 2011-10-24T00:00:00+00:00
Planned Dates: Start Date 2009-09-25T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Greater London
Sponsor(s) Prof Frances Cowan, Prof James Hakim