A psychological approach to understanding and treating bipolar disorder: investigating new cognitive mechanisms. (360G-Wellcome-088217_Z_09_Z)
Given the need to improve our understanding and treatment of bipolar disorder, this research investigates cognitive and emotional processes underlying mood instability. My previous research demonstrated that imagery has a powerful impact on emotion. I have developed a theory of mental imagery s amplification of emotion within bipolar disorder, proposing that this drives mood instability. The research will test hypotheses from this theory (and existing pilot-work), investigating whether biase s in mental imagery form part of the disorder s psychopathology. Treatment of imagery-related abnormalities will be explored. The research goals are to determine whether imagery-related abnormalities: (A) Occur in bipolar disorder and are specific to it; (B) Predict mood fluctuation; (C) Have causal significance; (D) Respond to cognitive behavioural treatment procedures? Each goal is the subject of a specific project. Project A compares imagery biases between clinical and non-clinic al groups. Project B prospectively studies patients with bipolar disorder using SMS (mobile phone) technology to track process changes over time. Project C experimentally manipulates imagery (in analogue samples) to determine whether hypothesised mechanisms have a causal role. Treatment development with patients in Project D will be informed by the experimental work. Project D includes a preliminary uncontrolled evaluation of the new cognitive behavioural treatment.
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Grant Details
Amount Awarded | 587035 |
Applicant Surname | Holmes |
Approval Committee | Clinical Interview Committee |
Award Date | 2009-06-17T00:00:00+00:00 |
Financial Year | 2008/09 |
Grant Programme: Title | Intermediate Clinical Fellowship |
Internal ID | 088217/Z/09/Z |
Lead Applicant | Prof Emily Holmes |
Partnership Value | 587035 |
Planned Dates: End Date | 2012-08-31T00:00:00+00:00 |
Planned Dates: Start Date | 2010-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | South East |
Sponsor(s) | Prof Christopher G Fairburn |