Fronto-temporal-dopaminergic networks in credit assignment and generalisation (360G-Wellcome-096587_Z_11_A)
The ability to use prior experience to aid processing when exposed to novel stimuli is vital for decision-making, and is an integral part of a number of models of learning. The aim of the proposed project is i) to elucidate the processes that allow generalisation from one set of circumstances to another, and ii) to establish the role of frontal and temporal lobe circuitry involved in this process, specifically in relation to fronto-temporal interactions and dopamine signalling. This will be achieved by conducting in vivo behavioural research in animal subjects, in conjunction with a variety of neural interference and imaging techniques. It is hypothesised that interactions between orbitofrontal cortex and the temporal lobe may be necessary for learning which elements of a stimulus most reliably signal the presence of reward, and subsequently generalising this information to novel contexts and stimuli. Further, this information should be reflected in phasicdopamine-encoded prediction errors within interconnected parts of the ventral striatum
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Grant Details
Amount Awarded | 93005 |
Applicant Surname | Cuell |
Approval Committee | PhD Studentships |
Award Date | 2013-03-25T00:00:00+00:00 |
Financial Year | 2012/13 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 096587/Z/11/A |
Lead Applicant | Mr Steven Cuell |
Partnership Value | 93005 |
Planned Dates: End Date | 2015-12-31T00:00:00+00:00 |
Planned Dates: Start Date | 2012-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | South East |
Sponsor(s) | Prof Andrew King |