Morphogenesis underlying choroid fissure fusion. (360G-Wellcome-099747_Z_12_Z)
Coloboma is a defect in the morphogenesis of the eye that results from failureof choroid fissure closure. It is among the most common congenital defects in humans and can significantly impact vision. However, very little is known about the developmental mechanisms regulating choroid fissure fusion. Therefore, I aim to resolve the cellular and molecular mechanisms underlying choroid fissure closure by high-resolution 4D confocal imaging of zebrafish retinal cells during fusion. In particular, I will investigate how cell cycle progression regulates the epithelial remodelling that accompanies fusion.
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Grant Details
Amount Awarded | 162047 |
Applicant Surname | Bazin Lopez |
Approval Committee | PhD Studentships |
Award Date | 2012-06-25T00:00:00+00:00 |
Financial Year | 2011/12 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 099747/Z/12/Z |
Lead Applicant | Ms Naiara Bazin Lopez |
Partnership Value | 162047 |
Planned Dates: End Date | 2017-03-31T00:00:00+00:00 |
Planned Dates: Start Date | 2012-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | Greater London |
Sponsor(s) | Prof Claudio Stern |