The metabolic regulation of hypoxia inducible transcription factors. (360G-Wellcome-102770_Z_13_B)

£127,447

We have recently identified a novel pathway for metabolic regulation of HIF1 alpha by the OGDHC1. To continue this new area of research, it is essential that we have the necessary funds to maintian our competitive edge within the field, without diverting resources from our successful ubiquitin studies. The initial research on HIFs has been conducted by a talented graduate student, Stephen Burr. The timing of this funding request is particularly important, as it will allow Stephen to transfer his skills with a sufficient overlap for a new postdoctoral researcher to pursue this project.

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Grant Details

Amount Awarded 127447
Applicant Surname Nathan
Approval Committee Science Enhancement Committee
Award Date 2016-12-05T00:00:00+00:00
Financial Year 2016/17
Grant Programme: Title Enhancement
Internal ID 102770/Z/13/B
Lead Applicant Prof James Nathan
Partnership Value 127447
Planned Dates: End Date 2019-02-01T00:00:00+00:00
Planned Dates: Start Date 2017-02-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England