Intracellular sodium and its effect on neuronal Gene Expression (360G-Wellcome-202469_Z_16_Z)
This project will involve investigating the effects of intracellular sodium on the gene expression in Dorsal root ganglion neurons. The key aims of the project will be to determine the role of sodium mediated signalling in neuronal gene expression. To determine this, high affinity sodium binding protein will be investigated; a cloned DNA construct of the protein will be transfected in to HEK (Human Embryonic Kidney) cells and then DRG neurons with a Nav1.7 knock out. The effect of low intracellular sodium concentration on expression of Penk will be assesed by analysis of the DRG neurons.
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Grant Details
| Amount Awarded | 1750 |
| Applicant Surname | Ebenebe |
| Approval Committee | Internal Decision Panel for C&S |
| Award Date | 2016-04-01T00:00:00+00:00 |
| Financial Year | 2015/16 |
| Grant Programme: Title | Vacation Scholarships |
| Internal ID | 202469/Z/16/Z |
| Lead Applicant | Miss Chimjika Ebenebe |
| Partnership Value | 1750 |
| Planned Dates: End Date | 2016-08-12T00:00:00+00:00 |
| Planned Dates: Start Date | 2016-06-13T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Greater London |