Investigating the association between genetic and epigenetic variability in immune genes and depression in young adults. (360G-Wellcome-207238_Z_17_Z)

£0

Depression is one of the most commonly occurring mental health disorder in student populations, and the general population. However, despite its prevalence the environmental and biological factors that cause depression, and the underlying pathophysiology of the disorder remain poorly understood. The current diagnosis of depression is largely subjective, and there are no clinically validated biomarkers that can be used to assist in diagnosis and treatment selection. Variability in genes encoding inflammatory cytokines has been linked to the aetiology of depression. The aim of this project is to identify candidate inflammatory biomarkers which could potentially be useful for diagnosis and treatment selection in depression. The main objectives will be to determine whether polymorphisms and DNA methylation patterns in the interleukin 1 beta (IL-1B) and Tumour Necrosis Factor alpha genes are associated with depression in the student population in Northern Ireland.

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Grant Details

Amount Awarded 0
Applicant Surname Harrigan
Approval Committee Internal Decision Panel
Award Date 2017-04-27T00:00:00+00:00
Financial Year 2016/17
Grant Programme: Title Vacation Scholarships
Internal ID 207238/Z/17/Z
Lead Applicant Mr Ruairidh Harrigan
Partnership Value 0
Planned Dates: End Date 2017-08-25T00:00:00+00:00
Planned Dates: Start Date 2017-06-26T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Northern Ireland