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University College London
£500 - £1,000
£1,000 - £5,000
Award Year:


A Two-day Conference on the Human Right to Health, Universal Health Coverage and Priority Setting. 27 Oct 2014

This grant would be used to fund a two-day conference exploring the various tensions between what the UN refers to as the progressive realisation of the human right to health, the international effort to secure universal health coverage and the inevitable need to set priorities between different treatments and services. The conference would bring together three research centres within UCL (the Institute of Global Health, the Institute of Global Governance and the Centre for Philosophy, Justi ce and Health) to hear new evidence from researchers, policy-makers and practitioners from both the UK and abroad. The conference would: i) explore existing policy drives towards HRH, universal health coverage and priority setting activities; ii) reflect upon conceptual and ethical tensions between such policies; and iii) assess the feasibility of solutions aimed at resolving this tension. The conference's main output would be a consensus statement, drawn up by Benedict Rumbold and circula ted to delegates before the meeting and discussed by attendees on Day Two of the conference itself, setting out the delegates thoughts on the next steps towards remedying the current conflict between HRH, the drive towards Universal Coverage and priority setting.

Amount: £4,760
Funder: The Wellcome Trust
Recipient: University College London

Public Engagement Provision 03 Dec 2014

The James Lind Alliance recently identified their 'Top 10' research prioritiesaccording to what stroke patients and their carers want. Cognitive therapies, long-term consequences of stroke and aphasia therapy were the top three priorities. My proposal will address all of these. Stroke patients with anomia and their families will be therefore be the main public beneficiaries of knowledge arising from this research. The results will inform them about brain and language recovery after stroke and potential new treatments that will directly improve their communication and quality of life.

Amount: £4,500
Funder: The Wellcome Trust
Recipient: University College London

Picking up ethical challenges within the humdrum of medical practice: does one ever get too used to it?. 15 Sep 2014

While phenomenological studies suggest that high degrees of expertise can enable some professionals to bypass cognitive processes altogether and intuitively see the solution to a problem, repeated exposure to the same scenario is conversely suspected to numb one's emotional sensitivity: [T]he horrible thing about all [...] officials, even the best [...] is not that they are wicked (some of them are good), not that they are stupid (several of them are quite intelligent). It is simply that they h ave got used to it. Is it the case that scenarios that would otherwise arouse powerful emotions (and hence alert our ethical sensitivity) can be sunk into the humdrum by the combined weight of professional identity and the habits entailed by it? Recent empirical studies have highlighted a wide variety of environmental and emotional factors shaping our moral attitudes, yet so far little attention has been paid to the impact of professional habits on such attitudes. This pilot study propos es to use highly immersive, virtual reality technology to enact -with 3D avatars- a seemingly routine medical scenario and test the participants' ability to discern indicators of some underlying ethical concerns.

Amount: £4,900
Funder: The Wellcome Trust
Recipient: University College London

Automatic anomaly detection for brain imaging triage and classification 15 Sep 2014

Modern brain imaging contains vastly more information than historical radiographs, yet its clinically informative output has remained the same: a radiologist’s verbal report. As the information content of imaging increases, a void has opened between what we expensively collect and what we actually use.This is both a lost opportunity, and an obstacle to the continued growth of brain imaging. Technology being developed by Dr Parashkev Nachev and colleagues at University College London seeks to close this gap by applying novel computer-assisted algorithms so as to exploit much more of the information in each scan than a verbal report contains. An automatic “anomaly map” for each scan, indexing the deviation from normality of each point, will assist radiological reporting, allow the application of computer systems that predict clinical outcomes from patterns of anomaly, and guide radiological triage and resource/performance management. The project aims to demonstrate the feasibility, robustness, clinical, and managerial value of the approach using a large collection of standard brain imaging, and to deliver a pilot system capable of translation into a full clinical product. Without changing any clinical pathways or adding new investigations, the system will improve radiological reporting and optimise radiological triage and management, while creating a scalable major new platform for computational imaging analysis.

Amount: £4,000
Funder: The Wellcome Trust
Recipient: University College London

Blastema formation and skeletogenesis during arm regeneration of the brittle star Amphiura filiformis: cellular and molecular characterization. 17 Jan 2014

<table> <tbody> <tr> <td>The aim&nbsp;&nbsp;of this research project is to understand the initial stages of brittle star &nbsp; arm regeneration in terms of stem cell involvement, cell specification and &nbsp; the earliest activation of the skeletogenic gene regulatory network. The &nbsp; brittle star is a marine organism with a unique capability for regenerating &nbsp; whole arms post-amputation or after injury. To determine whether the &nbsp; regenerative blastema, a mass of proliferative cells giving rise to the &nbsp; entire structure, is composed of stem cells or dedifferentiating cells, &nbsp; molecular tools will be employed for their characterization. Stem cell &nbsp; markers and lineage tracing techniques will be used to identify the nature of &nbsp; the cells, their origins and migratory behaviour. The regenerating arm of the &nbsp; brittle star is contains several skeletal structures and the second aim of &nbsp; this project is to understand the cohort of signalling pathways involved in &nbsp; the early specification of the cell lineages which will develop into this &nbsp; adult tissue. This will be achieved by using molecular techniques and a &nbsp; candidate gene approach for studying the genes that have already been &nbsp; well-characterised in the closely-related sea urchin, , for which a complete &nbsp; gene regulatory network for the embryonic development of skeletogenic cells has &nbsp; been published.</td> </tr> </tbody> </table>

Amount: £2,838
Funder: The Wellcome Trust
Recipient: University College London

'The importance of medical history: Transnational and cross-cultural perspectives on a multi-faceted discipline' conference to be held in Mumbai, India from 15th to 17th November 2007. 17 Oct 2007

The importance of medical history: Trans-national and cross-cultural perspectives on a multi-faceted discipline The proposed meeting will be the first of its type in the South Asian sub-continent - dealing with the important questions of historical method and historiography, from trans-national and cross-disciplinary perspectives; it will allow the audience access to a plethora of perspectives on how to study HOM. The projected audience will be university and college teaching, research and administrative staff of all grades, we well as undergraduate and post-graduate students, doctors, print and TV journalists, and independent researchers. A number of well-known scholars have agreed to attend the meeting, as they acknowledge the usefulness of an event like this in popularising HOM in an important education centre in Asia. These academics, who are attached to a number of Wellcome Trust-funded units, will draw upon an important item of their research - dealing with Europe, North America, Asia and further afield - to develop trans-national perspectives of how to study HOM. This meeting will engender a lot of discussion, which is critically important for an endeavour that seeks to provide new insights to post-and under-graduate teachers about important international developments in the discipline, and the most effective ways of teaching and carrying out research. Themes to be covered: History of pharmacology; Anatomy; Global trade and medicine; Medical genetics and gender; Medicine in the early modern period; Public health in 19th and 20th centuries; Global health programmes and disease eradication; War and medicine; International perspectives on rabies; Scottish doctors and British empire; Obstetrics and surgery; Cross-disciplinary perspectives on leprosy and empire; Hospitals; Medicine and 'witchcraft' in the early modern period; Healthcare in colonial Mumbai/India; Health of industrial labour; Oral histories of contemporary medicine and biological science; History of medical practice and multiple meanings of health.

Amount: £600
Funder: The Wellcome Trust
Recipient: University College London

New genetic knowledge and 'lay' expertise in cancer research: exmaining the cultural context of ethics and legitimacy. 31 Aug 2007

The project examines the social parameters of 'lay expertise' in relation to cancer research charities. It seeks to explore how lay consumers', fundraisers' or patients' perspectives and involvement are being incorporated within organisational practices and research agendas of charities that are funding research into cancer genetics. This initiative provides a vantage point from which to explore the pursuit and problems surrounding ethical legitimacy in the cultural context of the new genetics. This issue will be addressed by examining how emerging genetic knowledge and the development of lay expertise affect: The pre-existing balance between lay and expert and the nature of the 'gift' relationship in cancer research charities Attempts to incorporate lay perspectives and sustain 'hope' Social relations among different fundraisers and personhood in the context of lay expertise. The transactional social spaces of cancer research charities offer an important arena for ethnographic inquiry and therefore the opportunity to contribute to an understanding of science as a social process.

Amount: £4,814
Funder: The Wellcome Trust
Recipient: University College London