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University College London
£500 - £1,000
£1,000 - £5,000
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Created Out of Mind Hub award application support costs 31 Dec 2015

<p>This application follows an invitation from Wellcome staff to apply for a small grant to support costs relating to the development of our shortlisted outline application for the Hub award&nbsp;<em>Created Out of Mind: Changing perceptions of dementia through art and culture</em>. The proposed costs will be used to cover project management of our bid, art design and branding input from creative members of our hub bid team, and travel expenses relating to a series of meetings and workshops designed to build&nbsp;relationships, develop conversations and discuss key questions and proposed projects within and between existing and new team members.&nbsp;</p>

Amount: £4,766
Funder: The Wellcome Trust
Recipient: University College London

Sulfonium Salts as Precursors for 18F-labelling of Small Molecule PET Tracers 30 Jan 2015

<table> <tbody> <tr> <td>Positron &nbsp; emission tomography (PET) has become an invaluable tool for diagnostic &nbsp; imaging and medical research as it allows quantification of biochemical &nbsp; processes in vivo with unsurpassed sensitivity and specificity. Due to its &nbsp; near ideal physicochemical properties fluorine-18 is the radioisotope of &nbsp; choice for imaging applications with PET, yet the lack of efficient and &nbsp; practical methods for the incorporation of 18F limits the availability of &nbsp; clinically relevant radiotracers. In particular, late stage labelling of &nbsp; compounds bearing functional groups that are prerequisite to biological &nbsp; activity remains challenging. The Arstad group have recently developed a new &nbsp; radiochemical strategy for aromatic labelling of drug-like small molecules &nbsp; based on the unique reactivity of sulfonium salts with fluoride-18. In this &nbsp; project, we aim to investigate the structural requirements for labelling with &nbsp; 18F and to broaden the scope of the existing method by establishing &nbsp; complimentary synthetic routes. To demonstrate clinicalapplicability, the &nbsp; strategy will be used to simplify radiosyntheses of existing radiotracers, to &nbsp; improve the imaging properties of established tracers, and to develop novel &nbsp; diagnostic imaging agents. The work has the potential to open up new prospects &nbsp; for imaging applications with PET. Ultimately, the development of new &nbsp; diagnostic agents can lead to improved human health.</td> </tr> </tbody> </table>

Amount: £2,819
Funder: The Wellcome Trust
Recipient: University College London

'The importance of medical history: Transnational and cross-cultural perspectives on a multi-faceted discipline' conference to be held in Mumbai, India from 15th to 17th November 2007. 17 Oct 2007

The importance of medical history: Trans-national and cross-cultural perspectives on a multi-faceted discipline The proposed meeting will be the first of its type in the South Asian sub-continent - dealing with the important questions of historical method and historiography, from trans-national and cross-disciplinary perspectives; it will allow the audience access to a plethora of perspectives on how to study HOM. The projected audience will be university and college teaching, research and administrative staff of all grades, we well as undergraduate and post-graduate students, doctors, print and TV journalists, and independent researchers. A number of well-known scholars have agreed to attend the meeting, as they acknowledge the usefulness of an event like this in popularising HOM in an important education centre in Asia. These academics, who are attached to a number of Wellcome Trust-funded units, will draw upon an important item of their research - dealing with Europe, North America, Asia and further afield - to develop trans-national perspectives of how to study HOM. This meeting will engender a lot of discussion, which is critically important for an endeavour that seeks to provide new insights to post-and under-graduate teachers about important international developments in the discipline, and the most effective ways of teaching and carrying out research. Themes to be covered: History of pharmacology; Anatomy; Global trade and medicine; Medical genetics and gender; Medicine in the early modern period; Public health in 19th and 20th centuries; Global health programmes and disease eradication; War and medicine; International perspectives on rabies; Scottish doctors and British empire; Obstetrics and surgery; Cross-disciplinary perspectives on leprosy and empire; Hospitals; Medicine and 'witchcraft' in the early modern period; Healthcare in colonial Mumbai/India; Health of industrial labour; Oral histories of contemporary medicine and biological science; History of medical practice and multiple meanings of health.

Amount: £600
Funder: The Wellcome Trust
Recipient: University College London

New genetic knowledge and 'lay' expertise in cancer research: exmaining the cultural context of ethics and legitimacy. 31 Aug 2007

The project examines the social parameters of 'lay expertise' in relation to cancer research charities. It seeks to explore how lay consumers', fundraisers' or patients' perspectives and involvement are being incorporated within organisational practices and research agendas of charities that are funding research into cancer genetics. This initiative provides a vantage point from which to explore the pursuit and problems surrounding ethical legitimacy in the cultural context of the new genetics. This issue will be addressed by examining how emerging genetic knowledge and the development of lay expertise affect: The pre-existing balance between lay and expert and the nature of the 'gift' relationship in cancer research charities Attempts to incorporate lay perspectives and sustain 'hope' Social relations among different fundraisers and personhood in the context of lay expertise. The transactional social spaces of cancer research charities offer an important arena for ethnographic inquiry and therefore the opportunity to contribute to an understanding of science as a social process.

Amount: £4,814
Funder: The Wellcome Trust
Recipient: University College London