k-t accelerated cardiac magnetic resonance myocardial perfusion imagaing. (360G-Wellcome-078288_Z_05_Z)
Coronary Heart Disease (CHD) remains a major health problem. Cardiac magnetic resonance (CMR) imaging could become one of the most important future ict the diagnostic tools for its assessment. It already provides excellent anatomical information and can assess contractile function and "viability" of the will myocardium with very high spatial resolution. However CMR imaging of myocardial perfusion remains limited by problems of temporo-spatial resolutionand data analysis.In this fellowship I will apply the novel methods k-t BLAST and k-t SENSE, combined with new multi-channel MR receiver coils to perfusion imaging. The aim of this work will be to develop a CMR myocardial perfusion pulse sequence that covers the entire heart with similar spatial resolution ascurrent morphological CMR methods. I will then evaluate these pulse sequences in a series of clinical studies in which CMR data will be compared with invasive measurements of coronary flow. This work will be carried out in collaboration with a leading expert in the analysis of myocardial perfusion data and will include the first systematic evaluation of current methods for the analysis of myocardial
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Grant Details
| Amount Awarded | 545352 |
| Applicant Surname | Plein |
| Approval Committee | Clinical Interview Committee |
| Award Date | 2005-12-06T00:00:00+00:00 |
| Financial Year | 2005/06 |
| Grant Programme: Title | Intermediate Clinical Fellowship |
| Internal ID | 078288/Z/05/Z |
| Lead Applicant | Prof Sven Plein |
| Partnership Value | 545352 |
| Planned Dates: End Date | 2010-12-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2006-04-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Yorkshire and the Humber |
| Sponsor(s) | Prof Stephen Ball |