Expression and function of indoleamine 2,3-dioxygenase (IDO) following corneal transplantation. (360G-Wellcome-078732_Z_05_Z)

£201,302

This research is aimed at understanding the role of indoleamine 2,3-dioxygenas to what extent IDO expression has a role in the rejection of corneal allograft the factors that control IDO expression in corneal allograft rejection· whether over-expression of IDO in corneal allografts can prevent rejection· if over-expression of IDO in dendritic cells (DCs) will induce regulatory T-c if administration of IDO expressing DC can prevent graft rejection, and to com

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Grant Details

Amount Awarded 201302
Applicant Surname George
Approval Committee Immunology and Infectious Disease Funding Committee
Award Date 2006-02-09T00:00:00+00:00
Financial Year 2005/06
Grant Programme: Title Project Grant
Internal ID 078732/Z/05/Z
Lead Applicant Dr Andrew George
Other Applicant(s) Dr Daniel Larkin, Prof Myra McClure
Partnership Value 201302
Planned Dates: End Date 2009-10-17T00:00:00+00:00
Planned Dates: Start Date 2006-09-18T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Greater London