Developmental trajectories of unimodal and cross-modal attention deficits: the case of fragile X syndrome. (360G-Wellcome-079326_Z_06_Z)

£341,196

Fragile X syndrome (FXS) is caused by the silencing of a single gene affectingmultiple aspects of cortical development. In late childhood and adulthood, FXSis associated with striking inattention and hyperactivity. Our previous work revealed attentional deficits in toddlers and infants with FXS, highlighting very early onset of difficulties. Hitherto, deficits have been investigated using visual stimuli, but clinical evidence points to difficulties in other modalities, such as audition. Critically, attentional deficits in FXS may be exacerbated by the requirement of selecting multimodal real-world stimuli. Theprimary aim of the current proposal is therefore to investigate the impact of FXS on early developmental trajectories of visual and, for the first time, auditory and crossmodal attention, combining genetics, cognitive developmentaland psychophysical methods. More specifically, we aim to test the following hypotheses: i) developmental trajectories of unimodal and crossmodal attentionin fragile X syndrome will increasingly deviate from normal over early childhood (Goal A); ii) tasks resulting in conflict across modalities will

Where is this data from?

This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.

Grant Details

Amount Awarded 341196
Applicant Surname Scerif
Approval Committee Cognitive and Higher Systems Funding Committee
Award Date 2006-05-10T00:00:00+00:00
Financial Year 2005/06
Grant Programme: Title Project Grant
Internal ID 079326/Z/06/Z
Lead Applicant Prof Gaia Scerif
Other Applicant(s) Prof Annette Karmiloff-Smith, Prof Kim Cornish
Partnership Value 341196
Planned Dates: End Date 2011-07-31T00:00:00+00:00
Planned Dates: Start Date 2007-02-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East