The Newcastle Clinical Ageing Research Unit (CARU): a new facility for integrative and translational research on early assessment and treatment for older people. (360G-Wellcome-079394_Z_06_Z)

£2,666,358

We will establish an innovative Clinical Ageing Research Unit (CARU) as part of the Newcastle Campus for Ageing and Health (CAH), which will focus on developing early assessment and intervention strategies targeted at age-associated degenerative conditions. Research on ageing and age-associated disease is a Department of Health priority. Newcastle is one of the world's leading centres for ageing research with our researchers attracting over £38m in awards over the last 8 years and more than £12.5m in the last year. CARU will be intimately linked with cutting-edge research on underpinning mechanisms of ageing, including physical and functional links with the newly constructed Magnetic Resonance Centre that comprises a world class MR physics team and is being directed by a clinician with wide experience of MR research. This will optimise focus on clinical research whilst harnessing cutting edge development of MR techniques. CARU will provide exceptional opportunities for translational studies. Demographic trends mean that age-related health problems command increasing clinical attention. For the majority of these health problems, age itself is the single biggest risk factor. It is therefore of key importance to understand why the aged cell or organ becomes more vulnerable to pathology and what can be done to intervene at early stages before the less tractable end-stage pathology has developed. CARU is needed to provide the necessary specialist clinical research infrastructure for the expanding major research hub of the Institute for Ageing and Health (IAH) at Newcastle General Hospital, including extensive research on dementia and brain ageing. The CAH already includes the Henry Wellcome Laboratory for Biogerontology Research, IAH Research Laboratories (with Newcastle Brain Tissue Resource and aged animal units), and the MR Centre. CARU will support research in three of the UKCRN research networks (dementia and neurodegenerative diseases, diabetes and stroke) and have close links with the Directors of the Stroke and DeNDRoN Research Network National Coordinating Centres (Ford, McKeith).

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Grant Details

Amount Awarded 2666358
Applicant Surname Ford
Approval Committee Clinical Research Initiative Scientific Advisory Committee
Award Date 2006-05-11T00:00:00+00:00
Financial Year 2005/06
Grant Programme: Title Building/Refurbishment Grant
Internal ID 079394/Z/06/Z
Lead Applicant Prof Gary Ford
Partnership Name Clinical Research Infrastructure Initiative
Partnership Value 2666358
Planned Dates: End Date 2013-10-31T00:00:00+00:00
Planned Dates: Start Date 2008-11-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region North East