Investigation of the role of Neuromedin S, a newly identified powerful regulator of food intake. (360G-Wellcome-079527_Z_06_Z)

£236,661

Neuromedin S (NMS) is a newly identified powerful regulator of food intake. I will define the role of NMS in the control of appetite and the development of obesity. My key research goals are to: Determine the distribution of NMS and its response to changes in energy intake. Investigate the effects of CNS injection of NMS on food intake. Investigate the effects of NMS on known hypothalamic regulators of appetite. Examine the effects of NMS on long-term weight regulation using adeno-associated virus mediated gene transfer. These experiments will help to determine the importance of NMS in the hypothalamic regulation of food intake.

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Grant Details

Amount Awarded 236661
Applicant Surname Jayasena
Approval Committee Physiological Sciences Funding Committee
Award Date 2006-07-12T00:00:00+00:00
Financial Year 2005/06
Grant Programme: Title Research Training Fellowship
Internal ID 079527/Z/06/Z
Lead Applicant Dr Channa Jayasena
Partnership Value 236661
Planned Dates: End Date 2009-11-30T00:00:00+00:00
Planned Dates: Start Date 2006-12-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Greater London
Sponsor(s) Prof Sir Stephen Bloom