Functional investigation of Plasmodium falciparum var genes expressed at high levels in the tissue of Malawian paediatric malaria patients (360G-Wellcome-080964_Z_06_Z)

My current work has identified that a limited number of variants of the major further investigate the tissue-specific localisation of particular var/PfEMP1 determine if certain var/PfEMP1 types are associated with diagnoses such as ceinvestigate the phenomenon suggested by my current study that a restricted numdetermine which adhesive domains compose each variant, and which subtypes are express these adhesive domains and perform binding assays with candidate recepmeasure level of expression of adhesive domains in the tissues of a large numbber of patients to investigate associations with diagnosis and tissue localisation