Vitamin D and cardiovascular risk factors in early life. (360G-Wellcome-086449_Z_08_Z)
1) Examine cross-sectional associations between vitamin D, parathyroid hormone (PTH) and calcium and cardiovascular risk factors (blood pressure, fasting glucose, insulin, HbA1c. lipids and inflammatory markers) in children and adolescents. 2) Examine prospective associations of intrauterine (maternal pregnancy) and childhood (-age 9) vitamin D, PTH and calcium levels with later (-age 15-17) cardiovascular risk factors. 3) Use genetic variants robustly associated with variation in vitamin D status as instrumental variables to determine the causal association of variation in vitamin D with cardiovascular risk factors.
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Grant Details
| Amount Awarded | 139637 |
| Applicant Surname | Williams |
| Approval Committee | Immunology and Infectious Disease Funding Committee |
| Award Date | 2008-06-16T00:00:00+00:00 |
| Financial Year | 2007/08 |
| Grant Programme: Title | PhD Studentship (Basic) |
| Internal ID | 086449/Z/08/Z |
| Lead Applicant | Mr Dylan Williams |
| Partnership Value | 139637 |
| Planned Dates: End Date | 2012-12-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2008-10-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | South West |
| Sponsor(s) | Prof George Davey Smith |