The role of DNA methylation in heart failure (360G-Wellcome-086796_Z_08_Z)

£148,787

To investigate if hypertrophic stimuli alters Dnmt3b expression, in vitro and in vivo. To investigate in vitro, the role of altered DNA methylation on cardiac myocy1e and fibroblast survival, cell cycle, proliferation and senescence. To investigate in vivo, the role of altered DNA methylation on cardiac hypertrophy, dilatation and angiogenesis.

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Grant Details

Amount Awarded 148787
Applicant Surname Vujic
Approval Committee Physiological Sciences Funding Committee
Award Date 2008-08-29T00:00:00+00:00
Financial Year 2007/08
Grant Programme: Title PhD Studentship (Basic)
Internal ID 086796/Z/08/Z
Lead Applicant Dr Ana Vujic
Partnership Value 148787
Planned Dates: End Date 2012-09-30T00:00:00+00:00
Planned Dates: Start Date 2008-10-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England
Sponsor(s) Prof Sir Stephen O'Rahilly