The role of DNA methylation in heart failure (360G-Wellcome-086796_Z_08_Z)
To investigate if hypertrophic stimuli alters Dnmt3b expression, in vitro and in vivo. To investigate in vitro, the role of altered DNA methylation on cardiac myocy1e and fibroblast survival, cell cycle, proliferation and senescence. To investigate in vivo, the role of altered DNA methylation on cardiac hypertrophy, dilatation and angiogenesis.
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Grant Details
Amount Awarded | 148787 |
Applicant Surname | Vujic |
Approval Committee | Physiological Sciences Funding Committee |
Award Date | 2008-08-29T00:00:00+00:00 |
Financial Year | 2007/08 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 086796/Z/08/Z |
Lead Applicant | Dr Ana Vujic |
Partnership Value | 148787 |
Planned Dates: End Date | 2012-09-30T00:00:00+00:00 |
Planned Dates: Start Date | 2008-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | East of England |
Sponsor(s) | Prof Sir Stephen O'Rahilly |