Development of technology for combined PET and MR imaging. (360G-Wellcome-086900_Z_08_A)
This research is centred on developments and improvement to a combined Positron Emission Tomography (PET) and Magnetic Resonance (MR) scanner that acquires images simultaneously and is dedicated to pre-clinical imaging. I will develop a volume RF transmitter system combined with dedicated receiver coils for MR, which will provide uniform excitation for all studies, with a consistent minimum degradation for PET detection. These structures need to be integrated with life support and monitoring equ ipment compatible with both the PET and MR environment. I plan to directly compare schemes for MR attenuation correction with that determined by a conventional rotating radionuclide source. The prototype scanner has access for a conventional transmission scan system that I propose to adapt to operate in the dual scanner. The aim is to directly measure the gamma ray attenuation for comparison with predictions based on MR image data. I will investigate the use of motion sensitive MR pulse se quences to record organ movement during the PET scan. Sequences will be tailored to periodically include motion sensing sections that can subsequently be used to determine organ position during PET reconstruction. The goal is to demonstrate that simultaneous MR acquisition can be used to improve PET reconstructed.
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Grant Details
Amount Awarded | 88624 |
Applicant Surname | Hawkes |
Approval Committee | Physiological Sciences Funding Committee |
Award Date | 2011-11-30T00:00:00+00:00 |
Financial Year | 2011/12 |
Grant Programme: Title | Career Re-Entry Fellowship |
Internal ID | 086900/Z/08/A |
Lead Applicant | Dr Robert Hawkes |
Partnership Value | 88624 |
Planned Dates: End Date | 2013-03-31T00:00:00+00:00 |
Planned Dates: Start Date | 2012-04-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | East of England |
Sponsor(s) | Dr Thomas Carpenter |