Lactate and myometrial function: an investigation into the effects and mechanisms of action. (360G-Wellcome-089141_Z_09_A)
1. To determine the effects of extracellular lactate on force and calcium signalling in uterine smooth muscle 2. To examine lactate production and pH during normoxia and hypoxia 3. To determine the expression of lactate transporters (Mono-Carboxylate Transporter, MCT1-4) in the myometrium and how this changes with gestation in rats 4. In women having Caesarean Section (CS), to correlate measurement of lactate in myometrial capillary blood with indication for CS and in vitro contractility and lactate production.
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Grant Details
Amount Awarded | 14897 |
Applicant Surname | Hanley |
Approval Committee | Physiological Sciences Funding Committee |
Award Date | 2010-12-14T00:00:00+00:00 |
Financial Year | 2010/11 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 089141/Z/09/A |
Lead Applicant | Ms Jacqui-Ann Hanley |
Partnership Value | 14897 |
Planned Dates: End Date | 2013-09-30T00:00:00+00:00 |
Planned Dates: Start Date | 2010-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | North West |
Sponsor(s) | Prof Alexei Tepikin |