Lactate and myometrial function: an investigation into the effects and mechanisms of action. (360G-Wellcome-089141_Z_09_A)

£14,897

1. To determine the effects of extracellular lactate on force and calcium signalling in uterine smooth muscle 2. To examine lactate production and pH during normoxia and hypoxia 3. To determine the expression of lactate transporters (Mono-Carboxylate Transporter, MCT1-4) in the myometrium and how this changes with gestation in rats 4. In women having Caesarean Section (CS), to correlate measurement of lactate in myometrial capillary blood with indication for CS and in vitro contractility and lactate production.

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Grant Details

Amount Awarded 14897
Applicant Surname Hanley
Approval Committee Physiological Sciences Funding Committee
Award Date 2010-12-14T00:00:00+00:00
Financial Year 2010/11
Grant Programme: Title PhD Studentship (Basic)
Internal ID 089141/Z/09/A
Lead Applicant Ms Jacqui-Ann Hanley
Partnership Value 14897
Planned Dates: End Date 2013-09-30T00:00:00+00:00
Planned Dates: Start Date 2010-10-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region North West
Sponsor(s) Prof Alexei Tepikin