The use of embryonic dopaminergic tissues for Parkinson's Disease transplantation therapy. (360G-Wellcome-089638_Z_09_A)

£25,151

Overall aim: Improve dopamine cell yield and function in Parkinson's disease transplantation therapy (in rats) . Objective 1: Investigate the time course of dopamine neuron development in-vitro and in dopamine grafts. Objective 2: Characterise cell populations in rat and human embryonic dopamine grafts in a rat model of PD. Objective 3: Improve the survival of rat and human embryonic dopamine grafts and cultures. Objective 4: Determine the embryonic donor age in human embryos from which > 50% survival can be obtained (equivalent to E12 in rats).

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Grant Details

Amount Awarded 25151
Applicant Surname Fjodorova
Approval Committee Neurosciences And Mental Health
Award Date 2011-04-11T00:00:00+00:00
Financial Year 2010/11
Grant Programme: Title PhD Studentship (Basic)
Internal ID 089638/Z/09/A
Lead Applicant Miss Marija Fjodorova
Partnership Value 25151
Planned Dates: End Date 2013-09-30T00:00:00+00:00
Planned Dates: Start Date 2011-04-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Wales
Sponsor(s) Prof Vincenzo Crunelli