Exosome-based gene therapy for Huntington's disease (360G-Wellcome-092761_Z_10_A)

£35,540

1. To investigate the optimal strategies for exosome targeting to the brain in HD 2. To identify the optimal exosome RNAi cargo for suppression of htt expression 3. To evaluate brain-targeted exosomes for their ability to reduce htt expression in vivo and to prevent and/or reverse disease phenotype in a HD disease model.

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Grant Details

Amount Awarded 35540
Applicant Surname O'Loughlin
Approval Committee PhD Studentships
Award Date 2012-01-27T00:00:00+00:00
Financial Year 2011/12
Grant Programme: Title PhD Studentship (Basic)
Internal ID 092761/Z/10/A
Lead Applicant Ms Aisling O'Loughlin
Partnership Value 35540
Planned Dates: End Date 2014-09-30T00:00:00+00:00
Planned Dates: Start Date 2012-01-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East
Sponsor(s) Prof Andrew King