Disease risk in Madagascar. (360G-Wellcome-095171_Z_10_Z)

£1,151,019

The project will examine how environmental and social factors contribute to the risk from zoonoses in a developing country context, using rodents and rodent-borne disease in Madagascar as a model system. It will integrate analyses of archived data and samples from rodents, historic data on human plague incidence in Madagascar and new data on rodent and human infections in a diverse landscape. I will investigate how climate, habitat and landscape affect host-pathogen dynamics within the roden t populations, considering a range of pathogens with different transmission routes. In addition, I will explore how climate and landscape affect host and vector abundance and movement, key determinants of disease dynamics. Within humans, I will examine the relative importance of environmental and socio-economic factors for human exposure risk at different scales, determining whether relationships vary between pathogens. On the basis of the relationships detected, I will assess whether eff ective predictive risk models that exploit easily accessible data can be developed. I will produce maps of current risk and forecasts of risk under future climate change and deforestation rate scenarios. Results will be presented to health and environment sectors to raise awareness and explore potential disease reduction strategies

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Grant Details

Amount Awarded 1151019
Applicant Surname Telfer
Approval Committee International Interview Committee
Award Date 2011-04-07T00:00:00+00:00
Financial Year 2010/11
Grant Programme: Title Senior Research Fellowship Basic
Internal ID 095171/Z/10/Z
Lead Applicant Dr Sandra Telfer
Partnership Value 1151019
Planned Dates: End Date 2021-01-31T00:00:00+00:00
Planned Dates: Start Date 2011-08-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Scotland
Sponsor(s) Prof Christopher Secombes