RNA-binding proteins in health and disease. (360G-Wellcome-095518_Z_11_Z)
Our research focus on the role of RNA-binding proteins (RNABPs) in gene expression at different levels during the RNA processing cascade from splicing in the nucleus to translation in the cytoplasm. RNAs in cells associate with RNABPs to form ribonucleoprotein (RNP) complexes. There is a great variety of RNABPs, each with unique RNA-binding activity giving rise to a unique RNP for each RNA. They have a profound impact on cellular gene expression networks, affecting processes as diverse astranscription, pre-mRNA splicing, microRNA (miRNA) biogenesis and function andtranslation.
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Grant Details
| Amount Awarded | 1477149 |
| Applicant Surname | Caceres |
| Approval Committee | Science Interview Panel |
| Award Date | 2011-05-10T00:00:00+00:00 |
| Financial Year | 2010/11 |
| Grant Programme: Title | Investigator Award in Science |
| Internal ID | 095518/Z/11/Z |
| Lead Applicant | Prof Javier Caceres |
| Partnership Value | 1477149 |
| Planned Dates: End Date | 2011-09-30T00:00:00+00:00 |
| Planned Dates: Start Date | 2011-09-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | South West |