Exploring the impact of obesity and ageing on brain structure in a large cohort of healthy people. (360G-Wellcome-095692_Z_11_A)

£130,314

The funds are requested to provide support for the development of a program ofstructural neuroimaging data analysis, extending existing preliminary work carried out opportunistically under the support of the existing award. The flexibility provided by this award enabled me and my post-doctoral research (Dr Lisa Ronan) to develop preliminary ideas and perform exploratory analyses concerning the functional significance of traditional structural measures and of a novel measure that we have developed (Ronan et al, 2011). This has been extended both to empirically-supported theoretical insights about the significance of these structural measures (Ronan et al, 2012, 2014; Ronan and Fletcher 2015; Wagstyl et al 2015) and to direct applications to patient datasets (Ronan et al 2014). I have been especially excited at the implications that this developing work has for offering new ways of interpreting MRI measures of brain structure in health and disease.

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Grant Details

Amount Awarded 130314
Applicant Surname Fletcher
Approval Committee Science Enhancement Committee
Award Date 2015-06-08T00:00:00+00:00
Financial Year 2014/15
Grant Programme: Title Enhancement
Internal ID 095692/Z/11/A
Lead Applicant Prof Paul Fletcher
Partnership Value 130314
Planned Dates: End Date 2017-01-13T00:00:00+00:00
Planned Dates: Start Date 2015-07-14T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England