Computational Prediction of the Effects of Non-Synonymous SNPs on Protein Function (360G-Wellcome-097463_Z_11_Z)

£146,952

This bioinformatics research project will focus on the development of methods to predict the effects of non-synonymous single nucleotide polymorphisms on protein function. The project will evaluate current methods, develop a "meta-predictor" that combines the best methods and develop a new approach that includes data from recently published techniques in protein structure prediction and sequence analysis. The new predictor will be integrated with the Jalview multiple alignment workbench and be applied to novel whole exome and genome datasets produced by colleagues in Dundee.

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Grant Details

Amount Awarded 146952
Applicant Surname Giang
Approval Committee Molecules, Genes and Cells Funding Committee
Award Date 2011-08-31T00:00:00+00:00
Financial Year 2010/11
Grant Programme: Title PhD Studentship (Basic)
Internal ID 097463/Z/11/Z
Lead Applicant Ms Nancy Giang
Partnership Value 146952
Planned Dates: End Date 2015-08-31T00:00:00+00:00
Planned Dates: Start Date 2011-09-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Scotland
Sponsor(s) Prof Paul Crocker