Cambridge Stem Cell Institute. (360G-Wellcome-097922_Z_11_Z)

£4,314,068

This proposal is to facilitate creation of a world-leading centre for fundamental and translational stem cell research. The Cambridge Stem Cell Institute (SCI) will build upon previous Wellcome Trust and Medical Research Council funding by drawing together 30 research teams into a cohesive centre. These groups will ultimately be co-located in a purpose-designed 8000m2 facility to be constructed on the Cambridge Biomedical Research Campus. Platform technologies supported by a Centre grant will en able SCI to recruit and retain the most talented investigators and empower them to make ground-breaking advances in understanding stem cells and their medical applications. Fundamental research will focus at the molecular level on mechanisms of self-renewal, commitment, differentiation and reprogramming. Functional studies will address the role of stem cells in development, repair, ageing, physiology and pathologies including cancer. Disease-specific induced pluripotent stem cells will be exploi ted to unravel mechanisms of cellular pathogenesis and define drug targets. Strategies to mobilise endogenous stem cells for regeneration will be evaluated in animal models and in the clinic as will approaches based on cell transplantation. The Institute will provide comprehensive training in embryonic and adult stem cell biology and will seek, and offer unique opportunities for, bioindustry interaction and collaboration.

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Grant Details

Amount Awarded 4314068
Applicant Surname Smith
Approval Committee Strategic Awards Committee
Award Date 2012-04-17T00:00:00+00:00
Financial Year 2011/12
Grant Programme: Title Wellcome Trust Centre
Internal ID 097922/Z/11/Z
Lead Applicant Prof Austin Smith
Other Applicant(s) Dr James Fildes, Prof Benjamin Simons, Prof Oliver Brüstle, Prof Robin Franklin, Prof Tony Green
Partnership Name WT - MRC Council Cambridge Stem Cell Institute
Partnership Value 7388154
Planned Dates: End Date 2018-06-30T00:00:00+00:00
Planned Dates: Start Date 2012-07-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England