New insights from neonatal diabetes (360G-Wellcome-098395_Z_12_A)
What is the molecular genetic basis of severe beta-cell dysfunction resulting in neonatal diabetes? Defining known and novel causes will allow us to address these research questions: (i) What are the critical transcription factors for normal development of the human beta cell and other pancreatic cell types i (ii) What are the key genes and regulatory mechanisms for the maintenance of normal beta-cell number and normal insulin secretion in man? (iii) What is the function of the genes t hat cause neonatal diabetes in the beta-cell and other tissues?
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Grant Details
Amount Awarded | 1456000 |
Applicant Surname | Ellard |
Approval Committee | Science Interview Panel |
Award Date | 2012-05-15T00:00:00+00:00 |
Financial Year | 2011/12 |
Grant Programme: Title | Investigator Award in Science |
Internal ID | 098395/Z/12/A |
Lead Applicant | Prof Sian Ellard |
Partnership Value | 1456000 |
Planned Dates: End Date | 2019-09-30T00:00:00+00:00 |
Planned Dates: Start Date | 2012-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | South West |