Development of human induced pluripotent stem cells (iPSCs) in patients with neurodegeneration with brain iron accumulation (NBIA) (360G-Wellcome-099371_Z_12_Z)

£99,809

A Pathfinder Award to Dr Michael Hutton at Eli Lilly, in partnership with Professor John Hardy at UCL, will provide pilot funding for this Industriy-Academic partnership to work on the rare disorders termed Neurodegeneration with brain iron accumulation (NBIA).This is a group of rare, severe neurological disorders that are characterised by parkinsonism, cognitive decline and dystonia. The Award will fund the development of human induced pluripotent stem cells (iPSCs) cells offers a way to develop in vitro models of these diseases in the laboratory, without exact knowledge of the disease mechanism(s). The cell characteristics will enable these models to be amenable to drug treatment from the array of therapeutic compounds held by Lilly going forward.

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Grant Details

Amount Awarded 99809
Applicant Surname Hutton
Approval Committee Technology Transfer Challenge Committee
Award Date 2012-09-17T00:00:00+00:00
Financial Year 2011/12
Grant Programme: Title Pathfinder Award
Internal ID 099371/Z/12/Z
Lead Applicant Dr Mike Hutton
Other Applicant(s) Dr Mike Hutton
Partnership Value 99809
Planned Dates: End Date 2014-03-31T00:00:00+00:00
Planned Dates: Start Date 2012-10-01T00:00:00+00:00
Recipient Org: Country United States
Region International