Towards a high definition view of cytoskeleton remodelling by the bacterial pathogen Salmonella. (360G-Wellcome-101828_Z_13_Z)
What is the detailed biology underlying the intimate interaction of the bacterial pathogen Salmonella with the cytoskeleton of target host cells? In particular, (i) how are the signalling pathways that govern cytoskeletal rearrangements at the host cell membrane controlled by cooperating small GTPases, and (ii) how do secreted virulence effectors of pathogenic Salmonella act specifically and in concert on these signalling networks to effect cell invasion?
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Grant Details
Amount Awarded | 1902021 |
Applicant Surname | Koronakis |
Approval Committee | Science Interview Panel |
Award Date | 2013-07-10T00:00:00+00:00 |
Financial Year | 2012/13 |
Grant Programme: Title | Investigator Award in Science |
Internal ID | 101828/Z/13/Z |
Lead Applicant | Prof Vassilis Koronakis |
Partnership Value | 1902021 |
Planned Dates: End Date | 2021-12-30T00:00:00+00:00 |
Planned Dates: Start Date | 2014-01-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | East of England |