Targeted mRNA Trafficking in Pathfinding Axons of the Developing Visual System. (360G-Wellcome-102457_Z_13_Z)

£159,401

Building properly wired neural circuits involves guidance of axons towards synaptic targets in the brain. In the growth cone of pathfinding axons, targeted mRNA transport and localised translation is important for autonomously regulating navigational responses tocertain extracellular guidance cues. Still however, axonal mRNA trafficking remains poorly understood. We know very little about which mRNAs are differentially trafficked on guidance cue stimulation or mechanisms underpinning axonal mRNA transport. Using the well-characteriseddeveloping visual system as an experimental platform, this research proposal aims to explore the functional and mechanistic basis of targeted mRNA trafficking during axon guidance. We

Where is this data from?

This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.

Grant Details

Amount Awarded 159401
Applicant Surname Turner-Bridger
Approval Committee PhD Studentships
Award Date 2013-06-24T00:00:00+00:00
Financial Year 2012/13
Grant Programme: Title PhD Studentship (Basic)
Internal ID 102457/Z/13/Z
Lead Applicant Miss Benita Turner-Bridger
Partnership Value 159401
Planned Dates: End Date 2017-09-30T00:00:00+00:00
Planned Dates: Start Date 2013-10-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England
Sponsor(s) Prof Daniel St Johnston