An examination of the origin and mechanism of formation of the parasitophorous vacuole membrane in erthrocytic stages of the malaria parasite Plasmodium falciparum. (360G-Wellcome-103459_Z_14_Z)

£80,000

What is the originof the parasitophorous vacuole membrane(PVM) that is producedwhen the malaria parasite, Plasmodium falciparum, invades its host erythrocyte, andwhatare the contributions of host and parasite components, particularly those of the malarialrhoptry organellesininvagination of the erythrocyte membrane and subsequent establishment of thePVM?Thisis a long standing unresolved, question that has not received much attention recentlybut that is a fundamental aspectof Plasmodium biology. Newly developed genetic and imaging technologieswillbe applied that will allow new insight into this question.

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Grant Details

Amount Awarded 80000
Applicant Surname Sherling
Approval Committee WT/NIH Four Year PhD Programme Advisory Committee
Award Date 2013-12-09T00:00:00+00:00
Financial Year 2013/14
Grant Programme: Title WT/NIH Four Year PhD Studentship
Internal ID 103459/Z/14/Z
Lead Applicant Miss Emma Sherling
Partnership Name Wellcome Trust-NIH PhD Studentships
Partnership Value 80000
Planned Dates: End Date 2015-03-31T00:00:00+00:00
Planned Dates: Start Date 2014-09-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South West
Sponsor(s) Dr Anthony Holder