The cognitive thalamus: more than a relay. (360G-Wellcome-103722_Z_14_Z)
How do brain circuits support different but complementary aspects of event memory? The answer lies in distributed networks across the medial temporal lobe, prefrontal cortex and parietal cortex. Via their widespread connectivity, nuclei within the rostral thalamus support these memory networks. Indeed, one group (the anterior thalamic nuclei) forms the backbone of the extended hippocampal system, thought to be vital for episodic memory. We know remarkably little, however, about the nature of rostral thalamic information and how it impacts upon memory. We have recently discovered neurons in the rostral thalamus of freely-moving rats with hitherto unsuspected spatial properties. These cells are unlike any previously described in the region as they closely resemble place cells, boundary vector cells, and grid-cells (Fig.1A-F) found in hippocampal and parahippocampal regions. This discovery is set to transform our understanding of the region.
Where is this data from?
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Grant Details
Amount Awarded | 1070115 |
Applicant Surname | Aggleton |
Approval Committee | Science Interview Panel |
Award Date | 2014-04-01T00:00:00+00:00 |
Financial Year | 2013/14 |
Grant Programme: Title | Investigator Award in Science |
Internal ID | 103722/Z/14/Z |
Lead Applicant | Prof John Aggleton |
Other Applicant(s) | Prof Shane O'Mara |
Partnership Value | 1070115 |
Planned Dates: End Date | 2021-12-31T00:00:00+00:00 |
Planned Dates: Start Date | 2014-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | Wales |