Wellcome Trust Centre for Integrative Parasitology (360G-Wellcome-104111_Z_14_Z)

Modern approaches to parasitological research are multidisciplinary requiring many and varied expertise that a Centre best employs and exploits. Based upon polyomics and extensive bioinformatic/modelling platforms coupled with cutting edge imaging and novel, in house molecular parasitological methodologies the WTCMP will continue to play a leading role in tropical disease research. Primarily focussing on the molecular and cell biology of apicomplexan and trypanosomatid parasites, we address the major problems caused by parasitic infection in the tropics in a setting continuously strengthened by responsive investment in infrastructure and recruitment of promising group leaders. Translation is principally envisaged to be discovery and development of drug targets and vaccine candidates. WTCMP will continue to provide excellent training at pre-and post-graduate levels, mentoring across the career spectrum. WTCMP will accelerate the development of activities and partnerships in disease ende mic regions (DER) notably via the Wellcome Trust Liverpool Glasgow Centre for Global Health (WTLGCGH) initiative providing access to any relevant Glasgow expertise whilst allowing WTCMP-centred clinical engagement. Polyomics (particularly metabolomics) and modelling will be central to DER engagement allowing integration of our interactions with DER into a unified approach. WTCMP outreach will continue to inform the public of our activities and the problems we address.