Prime-Target Vaccination in Malaria (360G-Wellcome-104750_Z_14_A)
1. Can a more protective liver-stage vaccine against P. falciparum malaria be identified by assessing antigens using transgenic parasite technology combined with sequencing of parasite peptides eluted from MHC molecules? 2. Can this liver-stage vaccine be improved by combining it with an new virus-like particle-based anti-sporozoite vaccine? 3. How can these pre-erythrocytic components be efficiently integrated with anti-blood-stage and anti-sexual stage vaccine components to develop a hig hly effective multi-component malaria vaccine?
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Grant Details
Amount Awarded | 201600 |
Applicant Surname | Hill |
Approval Committee | Science Enhancement Committee |
Award Date | 2016-04-08T00:00:00+00:00 |
Financial Year | 2015/16 |
Grant Programme: Title | Enhancement |
Internal ID | 104750/Z/14/A |
Lead Applicant | Prof Adrian Hill |
Partnership Value | 201600 |
Planned Dates: End Date | 2017-11-30T00:00:00+00:00 |
Planned Dates: Start Date | 2016-06-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | South East |