Prime-Target Vaccination in Malaria (360G-Wellcome-104750_Z_14_A)

£201,600

1. Can a more protective liver-stage vaccine against P. falciparum malaria be identified by assessing antigens using transgenic parasite technology combined with sequencing of parasite peptides eluted from MHC molecules? 2. Can this liver-stage vaccine be improved by combining it with an new virus-like particle-based anti-sporozoite vaccine? 3. How can these pre-erythrocytic components be efficiently integrated with anti-blood-stage and anti-sexual stage vaccine components to develop a hig hly effective multi-component malaria vaccine?

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Grant Details

Amount Awarded 201600
Applicant Surname Hill
Approval Committee Science Enhancement Committee
Award Date 2016-04-08T00:00:00+00:00
Financial Year 2015/16
Grant Programme: Title Enhancement
Internal ID 104750/Z/14/A
Lead Applicant Prof Adrian Hill
Partnership Value 201600
Planned Dates: End Date 2017-11-30T00:00:00+00:00
Planned Dates: Start Date 2016-06-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East