Quantitative Proteomics Equipment for the Aberdeen Proteomics Facility. (360G-Wellcome-104941_Z_14_Z)

High throughput quantitative proteomics is an essential component of the contemporary experimental toolbox, and is critical for world-leading research programmes in the College of Life Sciences and Medicine at Aberdeen University. The Aberdeen Proteomics Facility was established 16 years ago and is manned by staff with vast experience of high quality proteomics service provision and training in quantitative proteomics, including SILAC and label-free approaches. The Facility provides a rang e of proteomics services to local and external users, including protein identifications, whole protein analyses, MALDI imaging and biotyping. To satisfy local research demand, the Facility needs more advanced equipment to extend our capabilities to high throughput, in-depth, quantitative analyses of specific proteomes, which is not currently possible in the Facility. Therefore, we are requesting a Q Exactive mass spectrometer and high throughput proteomic sample preparation robots. Our key objectives are: 1. To purchase a Q Exactive mass spectrometer and proteomics sample preparation robotics for the Aberdeen Proteomics Facility. 2. Exploit this equipment to provide cutting-edge proteomics services and bespoke proteomics training that empower a wide range of biomedical research programmes at Aberdeen University and other institutions. 3. To ensure the long term sustainability of this equipment by implementing appropriate cost-recovery mechanisms.