Multisensory Convergence and Integration in Thalamic and Cortico-Thalamo-Cortical Circuitry (360G-Wellcome-105241_Z_14_A)

£41,872

The thalamus occupies a unique position. All sensory information, but olfaction, travels through the thalamus before reaching its cortical destination. Furthermore, it has been found to be mediating communication between several cortical areas. However, the functional anatomy and role of such cortico-thalamo-cortical circuits are poorly understood in sensory processing. The thalamus has also been found to contain an intra-thalamic pathway, which appears to berelevant for sensorimotor integration. This project aims to elucidate the anatomy and functional role of such thalamic and corticothalamo-cortical circuits mediating multisensory convergence and integration. This is carried out in high spatial and temporal resolution using genetically targeted anatomical tracing and optogenetics. Such multisensory integration and convergence within the thalamus, could have deep implications for the understanding of early sensory processing and what sort of information the cortex is expected to receive from neurons earlier sensory pathways.

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Grant Details

Amount Awarded 41872
Applicant Surname Lohse
Approval Committee Internal Decision Panel for C&S
Award Date 2016-09-30T00:00:00+00:00
Financial Year 2015/16
Grant Programme: Title PhD Studentship (Basic)
Internal ID 105241/Z/14/A
Lead Applicant Dr Michael Lohse
Partnership Value 41872
Planned Dates: End Date 2018-09-30T00:00:00+00:00
Planned Dates: Start Date 2015-10-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East
Sponsor(s) Prof Andrew King