Characterising the viral ecology of native Irish bat species (360G-Wellcome-105340_Z_14_A)
The aim of this project is to determine the virome of native Irish bat species (order Chiroptera). Bat species have been widely connected to recent epidemic zoonoses, such as Ebola and SARS (Leroy et al. 2005, Li et al. 2005). Recent analyses of chiropteran viral ecology in South America and west Africa have revealed a novel poxvirus (Baker et al. 2013) and a nairovirus with clear zoonotic potential (Ishii et al. 2014). However, few studies of bat diseases have occurred in the British Isles; all but one has focused on European Bat Lyssavirus (EBLV) distribution, and none have taken place in Ireland. This study will use the VIDISCA-454 (Virus Discovery cDNA-AFLP (Amplified Fragment-Length Polymorphism) combined with Roche 454 high-throughput sequencing) protocol (de Vries et al. 2011), using biological samples taken from wild bat populations. This method has been developed for the detection of viruses in biological samples through extraction and sequencing of capsid-enclosed nucleic acids. Sequence assembly will then be performed and analysed for potential viral sequences. This method, and close derivatives, has been applied successfully to several clinical samples in detection of unknown pathogens, including a bovine hepacivirus (Baechlein et al. 2015) and chiropteran parvoviruses (Canuti et al. 2011).
Where is this data from?
This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.
Grant Details
Amount Awarded | 7156 |
Applicant Surname | Burkitt-Gray |
Approval Committee | Internal Decision Panel for C&S |
Award Date | 2016-09-30T00:00:00+00:00 |
Financial Year | 2015/16 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 105340/Z/14/A |
Lead Applicant | Miss Lucy Burkitt-Gray |
Partnership Value | 7156 |
Planned Dates: End Date | 2018-09-30T00:00:00+00:00 |
Planned Dates: Start Date | 2014-10-01T00:00:00+00:00 |
Recipient Org: Country | Ireland |
Region | Ireland |
Sponsor(s) | Prof Geraldine Butler |