PILOT - Cord Trial: Feasibility of conducting a trial evaluating timing of cord clamping for preterms in low and middle income countries (360G-Wellcome-105440_Z_14_Z)

This proposal addresses a series of questions necessary to establish the feasibility ofconducting the Cord Trial in low and middle income countries. Specifically, these are:2.1 What is current practice for timing of cord clamping at preterm, and term, births?2.2 What proportion of births meet the Cord Trial eligibility criteria (28-34 weeks gestation, or1–2 kg birthweight); of these what proportion can be identified before birth, and areappropriate clinical staff present to potentially recruit and deliver the interventions?2.3 For births at 28-34 weeks gestation (or 1-2kg birthweight), what is current practice forcare of the baby in the delivery room, and what is the outcome at hospital discharge?2.4 Can accurate information about timing of cord clamping, and care for the baby in the firstfew minutes after birth, be collected within routine clinical practice?2.5 Does gestation influence the volume and duration of placental transfusion?2.6 What are the potential barriers to recruitment and compliance with the trial interventions,and what are the views and attitudes of clinicians about timing of cord clamping?