CHARACTERISATION OF NOVEL FACTORS REGULATING CONE PHOTORECEPTOR DEVELOPMENT, FUNCTION AND SURVIVAL: TARGET BASED IDENTIFICATION OF NOVEL NEUROPROTECTIVE COMPOUNDS. (360G-Wellcome-106820_Z_15_Z)
My goal is to improve treatment options for devastating forms of blindness and to better understand the fundamental biology of photoreceptors. By characterising determinants of photoreceptor development, function and survival, I aim to identify novel neuroprotective compounds to treat vision loss. Cone photoreceptor neurons enable vision. My hypothesis is that cell signalling genes enriched in photoreceptors play critical functions in photoreceptor biology, and represent therapeutic targets for blindness. In this WT-NIIH studentship, I characterise the expression profile, interacting partners, function and therapeutic potential of factors enriched in cones using zebrafish, murine and induced pluripotent stem cell models.
Where is this data from?
This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.
Grant Details
| Amount Awarded | 80000 |
| Applicant Surname | Smith |
| Approval Committee | WT/NIH Four Year PhD Programme Advisory Committee |
| Award Date | 2015-01-12T00:00:00+00:00 |
| Financial Year | 2014/15 |
| Grant Programme: Title | WT/NIH Four Year PhD Studentship |
| Internal ID | 106820/Z/15/Z |
| Lead Applicant | Mr Andrew Smith |
| Partnership Name | Wellcome Trust-NIH PhD Studentships |
| Partnership Value | 80000 |
| Planned Dates: End Date | 2019-01-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2015-10-01T00:00:00+00:00 |
| Recipient Org: Country | Ireland |
| Region | Ireland |
| Sponsor(s) | Prof Breandán Kennedy |