Approaches to diagnosing dementia syndrome in general practice: Determining the value of gestalt judgment, clinical history and tests. (360G-Wellcome-108804_Z_15_Z)

£321,248

I will investigate whether an evaluation in general practice can have comparable test accuracy to a specialist opinion for diagnosing dementia in symptomatic elderly people. Objective 1: I will systematically review the test accuracy of general practitioners gestalt clinical judgment for the diagnosis of dementia in symptomatic primary care patients and, if indicated, perform a meta-analysis. My hypothesis is that the utility of the gestalt clinical judgment of general practitioners in diagn osing dementia is better than chance but inferior to specialist assessment. Objective 2: I will conduct an empirical, prospective, diagnostic test accuracy (DTA) study comparing GP gut feeling , blood tests, neuroimaging, index collection of cognitive tests suitable for GPs and specialist assessment to a reference consensus expert panel diagnosis. I will identify the most useful components of a diagnostic evaluation in general practice. My hypothesis is that a combination of brief cognitive tests adds diagnostic value to a GP's gestalt judgment. Objective 3: I will conduct exploratory qualitative research to evaluate the feasibility and acceptability of GP diagnosis of dementia for patients and clinicians, based on the set of tests that I identify as most useful.

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Grant Details

Amount Awarded 321248
Applicant Surname Creavin
Approval Committee Clinical Interview Committee
Award Date 2015-06-24T00:00:00+00:00
Financial Year 2014/15
Grant Programme: Title Research Training Fellowship
Internal ID 108804/Z/15/Z
Lead Applicant Dr Sam Creavin
Partnership Value 321248
Planned Dates: End Date 2021-03-13T00:00:00+00:00
Planned Dates: Start Date 2015-09-14T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South West
Sponsor(s) Prof Jonathan Sterne