A History of Randomized Controlled Trials. (360G-Wellcome-109324_Z_15_Z)

£1,320

I propose to visit a series of UK archives to collect material for my book on the history of randomized controlled trials (RCTs). This project focuses particularly on the interactions of science and policy in the history of RCTs, set in the major locations in which RCTs have been sponsored. The UK was the birthplace of RCTs and a global leader in trials in the 1950s. Thus, I am viewing materials from the scientists who conceptualized RCTs, as well as files on early UK RCTs and on the Medical Res earch Council support structure for such trials. I also am consulting meeting minutes of sub-committees on clinical trials that were established by the Committee on Safety of Drugs in 1963, and by the Committee on Safety of Medicines in 1968. I will explore the extent to which RCTs featured in discussions of drug safety and efficacy evaluation in these files. Additionally, I will consult files of the UK-based Cochrane Collaboration, which has played a critical role in the development of RCT meta -analyses since the mid-1980s. Finally, I will seek to identify material for future archival work on the history of RCTs in the UK.

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Grant Details

Amount Awarded 1320
Applicant Surname Bothwell
Approval Committee Humanities and Social Science, Small Grants Committee
Award Date 2015-06-22T00:00:00+00:00
Financial Year 2014/15
Grant Programme: Title Small grant in H&SS
Internal ID 109324/Z/15/Z
Lead Applicant Dr Laura Bothwell
Partnership Value 1320
Planned Dates: End Date 2015-07-31T00:00:00+00:00
Planned Dates: Start Date 2015-07-01T00:00:00+00:00
Recipient Org: Country United States
Region International