Conjugated Polymeric-Based Prodrug to enhance steroidal delivery into cartilages (360G-Wellcome-109455_Z_15_Z)

£73,028

Osteoarthritis (OA) is the key disease focus of the project, mainly through an improvement of the currently available drugs uptake. Additionally, a more selective distribution of the drug in the cartilage will reduce the required dose; both factors contributing to a reduction of the side effects associated with the drugs. The prevalence rate for OA is 11.3% or approximately 85 million people globally. It is expected to increase from 85 million in 2009 to 122 million in 2017. The main reason for this is the high incidence rate in the elderly population and the aging population trend. In addition, a rapid increase in the obese population will also contribute to an increase of the incidence of OA.

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Grant Details

Amount Awarded 73028
Applicant Surname Prokopovich
Approval Committee Pathfinders Assessment Group
Award Date 2015-08-25T00:00:00+00:00
Financial Year 2014/15
Grant Programme: Title Pathfinder Award
Internal ID 109455/Z/15/Z
Lead Applicant Dr Polina Prokopovich
Partnership Value 73028
Planned Dates: End Date 2018-03-31T00:00:00+00:00
Planned Dates: Start Date 2016-01-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Wales