Provision for Public Engagement (360G-Wellcome-110145_Z_15_A)
We will exploit our discovery of fundamental mechanisms regulating assembly in important single-stranded RNA viruses based on multiple, dispersed RNA-protein interactions (packaging signals, PSs) to: 1. Determine how genomic RNAs play regulatory roles in the mechanisms of virus assembly, maturation and host cell invasion. 2. Determine which viral and host components are needed to develop a quantitative systems understanding of assembly in vivo. 3. Analyse how viruses may evade anti-viral strategies targeting PS functions, triggering the occurrence of mutant strains. This paves the way for novel forms of anti-viral intervention.
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Grant Details
| Amount Awarded | 4937 |
| Applicant Surname | Stockley |
| Approval Committee | Science Interview Panel |
| Award Date | 2015-12-31T00:00:00+00:00 |
| Financial Year | 2015/16 |
| Grant Programme: Title | Provision for Public Engagement |
| Internal ID | 110145/Z/15/A |
| Lead Applicant | Prof Peter Stockley |
| Partnership Value | 4937 |
| Planned Dates: End Date | 2021-01-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2016-02-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Yorkshire and the Humber |