Alpha-GABa receptor modulators for the treatment of cognitive impairment associated with Huntington’s disease (360G-Wellcome-110377_Z_15_Z)

£1,478,688

Huntington's disease (HD) is a fatal genetic disease characterised by a movement disorder that is accompanied by a decline in cognitive function and changes in mood and behaviour. The decline in cognitive function may precede the movement disorder by a decade or more and is a very important component of the functional disability associated with HD. There is, however, no effective treatment for enhancing cognitive performance in HD. The Professor John Atack from the University of Sussex aims to identify novel drugs that can enhance cognitive performance in subjects with HD and thereby address a large unmet medical need.

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Grant Details

Amount Awarded 1478688
Applicant Surname Atack
Approval Committee Seeding Drug Discovery Committee
Award Date 2015-10-22T00:00:00+00:00
Financial Year 2015/16
Grant Programme: Title Seeding Drug Discovery Award
Internal ID 110377/Z/15/Z
Lead Applicant Prof John Atack
Partnership Value 1478688
Planned Dates: End Date 2020-07-31T00:00:00+00:00
Planned Dates: Start Date 2016-07-11T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East