Persistence of Zika virus in body fluids of patients with Zika virus infection (360G-Wellcome-206522_Z_17_Z)

£126,798

The purpose of this study is to assess the presence and duration of infectious Zika virus (ZIKV) and related markers (ZIKV-specific RNA, antigen, antibodies, T-cell response, and innate immunity) in blood, semen, saliva, oral fluid (saliva and crevicular fluid), urine, vaginal secretions, menstrual blood, rectal swab, tears, sweat and breast milk of infected individuals who present to clinics during acute illness and convalescence, and in comparison to their symptomatic or asymptomatic household contacts. To also relate these parameters to host immunity over time and across different body fluids, to socio-demography as well as other host and environmental factors.

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Grant Details

Amount Awarded 126798
Applicant Surname de Filippis
Approval Committee Internal Decision Panel
Award Date 2017-05-15T00:00:00+00:00
Financial Year 2016/17
Grant Programme: Title Zika Initiative Award
Internal ID 206522/Z/17/Z
Lead Applicant Dr Ana de Filippis
Partnership Name Zika Research Support Initiative
Partnership Value 253597
Planned Dates: End Date 2018-07-03T00:00:00+00:00
Planned Dates: Start Date 2017-04-03T00:00:00+00:00
Recipient Org: Country Brazil
Region International