Assessment of Biomarkers of Reperfusion Injury Relating to Effectiveness of Stroke Treatments (360G-Wellcome-206885_Z_17_Z)

The research aims to quantitatively assess biomarkers of reperfusion injury after induction of focal cerebral ischaemia in rats by occluding the middle cerebral artery, subsequently reperfusing it for 2 or 4 hours. The brain sections of the rats are then analysed to look at the extent of haemorrhage with the dysfunction of the blood brain barrier which causes biomarkers to be released. The results can then be used to measure which biomarker indicate greater reperfusion injury as well as the effectiveness of different reperfusion strategies in stroke.

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Grant Details

Amount Awarded 0
Applicant Surname Chiang
Approval Committee Internal Decision Panel
Award Date 2017-04-27T00:00:00+00:00
Financial Year 2016/17
Grant Programme: Title Vacation Scholarships
Internal ID 206885/Z/17/Z
Lead Applicant Mr Zhi Wen Chiang
Partnership Value 0
Planned Dates: End Date 2017-07-14T00:00:00+00:00
Planned Dates: Start Date 2017-05-15T00:00:00+00:00
Recipient Org: Country Ireland
Region Ireland