Ocular Drug Delivery by Using Preformed Biodegradable Implants (360G-Wellcome-207225_Z_17_Z)
Glaucoma can result in damage to the optic nerve and vision loss, which is a leading cause of blindness. Eye drops is the most commonly used treatment for glaucoma in clinic. This treatment is associated with low bioavailability of the applied drug and unpleasant side effects resulted from frequent administrations. This study aims to develop novel ocular drug delivery systems using drug-loaded biodegradable implants for the treatment of glaucoma. In this study, drug-loaded implants composed of poly(lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) will be formulated. The structure, thermal properties, mechanical properties, degradation behaviors and in vitro drug release profiles of the implants will be further investigated. These drug-loaded implants can provide a sustained release of the incorporated drug, reduce the burden of frequent administration and finally improve patient compliance.
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Grant Details
| Amount Awarded |
0
|
| Applicant Surname | Ting |
| Approval Committee | Internal Decision Panel |
| Award Date | 2017-04-27T00:00:00+00:00 |
| Financial Year | 2016/17 |
| Grant Programme: Title | Vacation Scholarships |
| Internal ID | 207225/Z/17/Z |
| Lead Applicant | Miss Elizabeth Ngiik Hung Ting |
| Partnership Value | 0 |
| Planned Dates: End Date | 2017-08-11T00:00:00+00:00 |
| Planned Dates: Start Date | 2017-06-12T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Northern Ireland |