Determining the temporal stability of an immunoscore in high grade serous ovarian cancer (360G-Wellcome-207299_Z_17_Z)
The importance of the immune system in determining the behaviour of a cancer is only now becoming clearly understood. Recent data in patients with ovarian cancer have shown a positive correlation between tumours that have pre-existing intraepithelial T cells at diagnosis and extended life span of the patient. Such information may have both prognostic and predictive implications but a key tool required for the unlocking of this knowledge is a robust immunoscore. Imunoscores are simple scoring systems based on the presence or absence of immune markers including CD4, CD3 and CD45RO. The aims of this research project are to evaluate the temporal stability of the immunoscore using paired samples measured at primary presentation and then after three cycles of chemotherapy thus informing how the immunoscore can be incorporated into clinical research and practice.
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Grant Details
| Amount Awarded |
0
|
| Applicant Surname | Johnson |
| Approval Committee | Internal Decision Panel |
| Award Date | 2017-04-27T00:00:00+00:00 |
| Financial Year | 2016/17 |
| Grant Programme: Title | Vacation Scholarships |
| Internal ID | 207299/Z/17/Z |
| Lead Applicant | Miss Paige Johnson |
| Partnership Value | 0 |
| Planned Dates: End Date | 2017-08-25T00:00:00+00:00 |
| Planned Dates: Start Date | 2017-06-26T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | North West |